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Friday, April 28, 2017

Conditions Causing Skin Hyper pigmentation



Sometimes in medical practice patients presents with skin hyperpigmentation or pigmented spots. There are many underlying different causes and they are briefly discussed here:

1. Endocrine Disorders
  • Addison’s disease
  • Cushing’s syndrome
  • Acromegaly
  • Nelson’s syndrome
  • Pregnancy
  • Porphyria
2. Renal Failure

3. Cirrhosis

4. Haemochromatosis

5. Nutritional Causes:
  • Vitamin B12 deficiency
  • Pellagra
6.. Amyloid

7. Acanthosis nigricans


8. Lymphoma

9. Peutz-Jegher’s syndrome (perioral)

10. Drugs
  • Amiodarone
  • OCP’s
  • Minocycline

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